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how can i rapidly remediate thc from cbd in my hemp extract using flash column chromatography

by Prof. Jensen Hartmann DVM Published 1 year ago Updated 3 months ago

The next step in the process is to concentrate the matrix by removing the solvent so that it can be injected on the chromatography column. The chromatography in this case is tuned to remove THC from the remaining CBD that is left in the supernatant. The recovered matrix and CBD is then added back to the CBD crystals.

Full Answer

How do you remove THC from hemp?

Chromatography is arguably the most popular option of THC remediation. There are various types of chromatography, but the most-used type is called flash chromatography. It is expensive, which is a deterrent for some. However, it does achieve a 99.9% removal of THC.Sep 3, 2020

How do you separate THC from CBD oil?

Chromatographic methods such as flash chromatography and CPC use solvents and a stationary phase to fractionate the cannabinoids from one another. In these processes, the THC is isolated and removed from the other cannabinoids.Apr 22, 2020

What is THC remediation?

THC remediation is the process of separating and removing THC molecules in hemp oil production and is an important step for CBD oil and product sales and compliance. Consistently producing oil with less than 0.3% THC opens many doors in the hemp market to take advantage of growing demand.

Is THC or CBD more polar?

CBD elutes more quickly than THC as it contains alcohol rather than an ether functional group at relatively the same position in the molecule, causing it to be slightly more polar.Feb 1, 2021

What is hemp remediation?

Remediation refers to any process by which non-compliant hemp (THC concentration > 0.3%) is rendered compliant (THC concentration ≤ 0.3%).Jan 15, 2021

What is dilution in cannabis extract?

Dilution is a common and low-tech method of lowering the level of THC in the extract. Dilution can be a cost-effective and straightforward method of THC remediation compared to other high-tech methods.

How to reverse phase chromatography?

Here is a quick look into how reverse phase chromatography works: 1 The extract is pumped into a column featuring stationary phase media. 2 As the crude oil passes through the media, the THC and CBD interact differently with it making the CBD move through the media at a quicker rate. 3 CBD exits the column before the THC and is collected separately. 4 The THC exits the column later and can be destroyed (if necessary).

What is SFC in THC?

Supercritical fluid chromatography (SFC) can produce great results in THC remediation. Generally, lower solvent amounts are needed compared to conventional systems. However, SFC can also result in large losses of minor cannabinoids and a lower yield of crude oil.

What is HPLC in chemistry?

HPLC is a type of liquid chromatography that uses less solvent and has shorter run times than flash chromatography. HPLC can be the ideal solution for manufacturers looking to scale their operations. HPLC is a common method of testing the potency and purity of cannabis samples.

Is THC removed from hemp?

As the cannabis industry continues to grow and exceed market expectations, THC removal will continue to be a significant step in the supply chain of hemp-derived extracts and infused products. Knowing how to remove THC without reducing CBD yield will determine the success of extraction operations.

In Summary

Geoff Todosiev & Michelle Armstrong join us on the HempList this week with Interchim. Hosted By Chase Nobles, Founder of Kush.com Interchim manufactures and sells high capacity columns & flash chromatography systems for hemp / cannabis cannabinoid extraction, and remediation.

Transcript (auto-generated)

hey everybody Chase Nobles here founder over at kush.com super excited for the show today we’ve got Geoff and michelle from Interchin here on the show with us today how are y’all doing great another one of the day beautiful day thank you for having us hello of course it’s a beautiful day up here in seattle it’s finally 70 degree weather hopefully summer spring is is here because we made it through a long winter with coven in the rain so excited for it where where are you at jeff where where are y’all located so i’m envious of you because it’s 70 there i’m in southern california and we’re barely breaking 60 right now so i don’t know what’s going on but yeah i’m based in los angeles right on and then out of boston yeah i’m like based in the boston area and there’s a little snowflake for the forecast for tomorrow don’t i don’t want to hear about the 70 degrees [Music] so we’re getting all kinds of different weather weather here um great well let’s just do a brief intro jeff how did you end up starting this company what what drove you into the uh chromatography business and the the the extraction equipment business how did you get here that’s a good question um i’ve been in the chromatography industry for almost 30 years and um just with various companies i um started out with a pretty well established company called phenomenox then i started my own business medicam had that sold it for about 10 years later and then i started out with intershim because they wanted to have a u.s presence so we started the intershim um business here in southern california um as the american north and south american representative for intersting headquarters in france um and then about five years ago i started you know being in southern california i started looking at cannabis as a potential market for chromatography and was working with some garage operations as they were then um and especially in southern california i’m sure you’ve seen the whole whole spectrum of businesses in the cannabis industry down there yeah yeah i’ve seen it all and um yeah so then after seeing the potential of chromatography with the cannabis market we started developing applications so that’s that’s the long and the short of it got it and jeff you know having founded your own business and then joining up with a company like interchan based out of france has that been a challenge what’s that been like working with you know an internationally headquartered business as amer you know as the american operations in a highly regulated space or sometimes completely unregulated space what’s that been like for you it’s it’s been a challenge um you know some of the challenges are simply cultural because in you know michelle and i over the years um we’ve learned that well we better build up our inventory in may because nothing’s going to happen in july in france you know the whole country pretty much shuts down predicting for summer holidays in july and august but we manage that that’s a managed process that we can do as far as the cannabis space though that’s um you know we just made it work it’s just a matter of identifying all right where what do we have to do in order to get these products to work in the cannabis space because they’re very different than what we’re used to in big pharma you know big pharma they have certain expectations for deliveries you know two to three weeks six to eight weeks that’s fine not in the cannabis space we need to deliver from inventory so we just maintain a lot of inventory to satisfy that and then we also do material modifications to the instruments to make them more usable in the cannabis space so it’s software and hardware hardware modifications to make it work in a high throughput production environment right yeah i would imagine the the throughput on a hemp extraction facility is much different than the throughput you know in the pharma space um just because you’re you’re you’re literally turning a crop into an oil um what are the differences there and what are some of those material changes that you’ve you’ve had to make to the equipment yeah from a throughput perspective you know in pharma we’re used to the expectation there is micrograms in milligrams um where in the cannabis space of course we’re talking not just kilos but multiple kilos per day you know that’s what we need to achieve and then we can do it so it’s just a matter of making those changes to the software to make it more usable in that environment and as far as the software it’s just a matter of you know tailoring it to a production environment where in pharma we’re used to research and development and some we do have some in production but on a on a small scale um and then the hardware modifications are just things have to be bigger you know the the largest columns that we have in pharma are you know about this big um whereas what we do in what we do in cannabis they’re eight and a half feet tall you know these are big pieces of hardware that we’re moving now as opposed to what we do in farming so those are the probably the two biggest differences now when it comes to chromatography there’s a lot of use cases right everything from my cannabinoid isolation to thc and pesticide remediation michelle what do you do at interchime and and how do you work with the customers to solve their specific needs sure yeah so i’ve been um with intershim for about 12 years now um and so pretty nice oh yeah yeah it’s been a little while no so we um we have a full sop for um thc remediation and pesticide remediation so it’s you know it’s really turnkey which is really nice and then you know i support the clients who um you know basically have like questions on the sop and um you know i do the the training for them um and we do we have remote access too so it’s really nice to you know there’s um if there’s new people um coming on board to that facility i can train them you know just over the computer and whatnot so um it’s been it’s been you know with covet and everything like that we’ve found ways to you know still be able to be very flexible in that aspect of things but uh yeah supporting yourself yeah hopefully we’re almost past that i the whole covet you know getting a vaccine i just got my second shot yesterday i’m feeling good right now fingers crossed because i’m getting on a plane tonight but hopefully hopefully i stay lively here uh through today but for thc remediation and pesticide remediation and i know you’ll both specialize in kind of different realms of that but for thc remediation specifically michelle you know how how do people work with that i imagine that you’re isolating the thc molecule and taking it out what does that look like on a large scale um whenever you have let’s say 10 kilos that are over the thc allotment that they’re allowed to have yeah so it’s um it’s all about like the process so after winterization they do their distillation and then after they do the distillation um we basically have a detailed sample prep on what they to do with that distillate before it goes on to the the purification column so um basically you know the the cleaner the distillate they’re putting on the higher the yield and you know the better the output that they get so really um you know we’ve taken care of being able to prep them to what to put onto their onto the system to be able to get the optimize the best results so great and yeah and jeff let’s talk about something that’s really plaguing the space pesticides um you know we’ve run into issues with pesticides it seems like this plant sucks any pesticides out of the ground and puts it into the end product when it comes to equipment manufacturing you deal with all kinds of things like was the product actually dirty was there something that was that had pesticides in it that ran through before um was the equipment manufactured in a not a clean environment what are you seeing out there and how’s it impacting the you know the clients and the large scale extractors that you all work with yeah it’s um actually the pesticide application is the first one that we developed because it is such a problem you know um and it’s heartbreak too it can be business ruining for a lot of people out there oh yeah and even those that are taking all the right precautions and you know you know one example is you know from the beginning you know where are we going to farm where are we going to cultivate you know if you’re an outdoor grower okay you test the soil and it’s clean say great plant the crop extraction test and sure enough you’ve got a hot product and that’s just because those pesticide levels are so low in the soil they’re not detected using standard techniques but when you plant the crop that crop it basically the the cannabis plant it’s basically a sponge it’s soaking up all the contaminants in the soil and it’s concentrating them and then when you go to extraction that’s further concentration so you basically got two concentration processes which are building up higher and higher levels of the contaminants and then now you’ve got a crude extract or a distillate that’s you need to be cleaned up and we actually have a really high throughput application to support that and it removes the majority of the pesticides so i imagine the challenge is really great though because there’s not just hundreds of pesticides out there there’s thousands of different pesticides out there it seems like how do you come up with the form you got to isolate all of them or the majority of them what does that look like from a scientific standpoint it’s um it’s we’re just using our knowledge of chromatography in the pharmaceutical and the natural products industry and we’re applying that to what is what are the what the challenges are in cannabis so as far as the pesticides go thankfully the vast majority i would say greater than 90 we’ve got a very high throughput application for that now for those remaining 10 and these are really rare pesticides that are really not seen that much that remaining 10 we’ve got another technique it’s not as high throughput but it’s still effective wow so so whatever comes across your table your equipment can potentially hopefully do a really good job of taking it out because you know i’ve had conversations with people that have you know shut down because of an issue like this and uh not been able to find somebody that can remediate whether it’s thc or or pesticides but pesticide seems to be the harder one so um congratulations on that can you tell us a little bit about the specific equipment and process to um remediate pesticides like the actual product that you sell and how it works because you know we’ve all had to learn a lot of science being in this space but not all of us are scientists right yeah completely understood so we we take that into consideration and that’s why as michelle mentioned you know we have very detailed sops so that we can make you an expert in chromatography as long as you know as long as you’re following the sop you have an expected result that you can be achieved um it’s actually what we’re doing we’re just taking our standard equipment that we sell into the pharmaceutical industry and then we’re bundling it with the media that goes into the chromatography column that is you know the the media in the column that really is the heart of the system because that’s what gives you the power to separate or to remediate the compounds that you’re you’re dealing with um and then the it’s also the solvents that are going through the problem you know we’re always trying to um gear our methodology where we’re using just solvents and no water because in the solvent recovery process water’s a real problem um so the pesticide remediation application no water you know for the 90 method for the other 10 yeah in some cases we’re going to have to use water but that’s really how we tailored our methodology to make um really you know the majority of our installations in cannabis there’s limited or really no knowledge of chromatography so you know making the detailed sops as michelle mentioned has really it helps us quite frankly because we can deliver something and you know day one you’re producing clean material and then using um you know continued support after we’ve done the installation we’ve had you know this year especially we adapted and you know team viewer is a great application for us because it allows us to you know monitor and work with the customers in real time and they’re they definitely see that benefit so it’s something that has uh has really helped us quite frankly and so um going back to i want to zoom out just a little bit further you know i think we’re assuming everybody knows exactly what you’re talking about whenever you say media or media and the column um what are all the pieces that people are working with here when it comes to an inner chin product you know everything from the calm the media to the the actual collection units what is that what does it look like can you draw a picture for everybody that doesn’t know exactly what we’re talking about here when it comes to remediation and and isolation [Music] okay so you know what chase does it make sense if i bring up a powerpoint slide so they can actually see a visual yeah do you have it in front of you that would be great um give don’t worry so basically um that each system is compromised of is basically an hplc pump so it’s basically um you know a high pressure pump that can be able to handle um you know the high throughputs of the the mobile phase which is the solvent the liquid that’s going through the system and then you have so you have the pump and then you have a uv detector so the uv detector is actually um is what’s showing us on the computer which is basically the graph is chromatograph that you’re seeing so basically depending on the time and the mobile phase and the distillate going through the column the uv detector is going to basically see a peak or basically sense a cannabinoid coming off of the column and then you’ll be able to see a peak to basically show that represent that and then also on the system is a fraction collector so basically it’s going to automatically start collecting the cannabinoids or the products that you want to collect based on time or um on inflection depending on what you’re what you want to do there so your products actually testing the material that comes out and and being able to isolate the piece that you’re seeing and the the the molecules that you’re seeing as it goes is that what you’re saying michelle well so the uv detector is the way of basically um to trigger the collection or basically to show you that a cannabinoid is coming out for identification to know what is coming out then that’s where hplc comes in handy so having in-house analytical is super helpful of course and i’ve seen a lot of people have to set those up jeff let’s take it over to you show us what you’re working with uh i just want to keep it educational because so much of this you know a novice farmer that’s well not a novice farmer but a farmer that’s never worked with hint before has never had to deal with an issue like this and so really break it down and for me because i i want to learn as much as i can even though i’ve had these conversations i still get confused so yeah break it down for us jeff show us show us what we’re working with okay so this is basically what michelle just described um we’ve got a pump right here we’ve got the column and then we’ve got this detector and then the detector is going to detect and it’s either going to send the sen the the liquid to to waste or we’re going to collect it okay so before the pump we’ve got a couple solvents you know usually you know um a couple of organic solvents something like heptane ethyl acetate um if we’re doing the thc remediation that would be a combination of methanol and water so that this is a this is a precision hplc pump um so it if we tell it to deliver you know 63 of a and uh the remainder 37 b it will accurately deliver that and that’s really important for chromatography that allows us to set up a an sop with a production method that’s repeatable so that way if you’re if all of your products going in you know your sample is consistent the pump will deliver that consistent result so we’re actually loading the sample with the pump onto the column as well so what’s typically done is you’re mixing these solvents you’re pumping and you’re pumping that liquid through the column and then when it’s ready okay when it’s equilibrated then the sample is pumped onto the column and then as the sample travels through the column the media in the column has or the sample the various components in the sample have different attractive forces for the media in the column so those that have no attractive force will move through at the same rate of speed as the flow that you’ve introduced but those that have a stronger attraction will get slowed down and that’s how you separate things so for our txt remediation thc moves slower okay so we’re getting all of the the good stuff out first the cbg the cbd etc and then we’re keeping we’re trapping that thc until we want to push it off so that’s what we’re doing we’re separating the thc from cbd and detecting that and then collecting it or sending it to ways beautiful thank you so much for pulling that up that was no that was great i think that solved a lot of the uh the challenge when it comes to talking about equipment because you know uh like i said we all have had to learn a lot of science but we’re not scientists so drawing a picture that uh you know a 10 year old can understand makes it so much easier i think for everybody out there to think about what the what what equipment they might need or should be thinking about or at least if they’re talking to somebody to know what the equipment does and have an understanding because a lot of times people are you know doing splits or tolling and you have to have a really trusting relationship with the person that you’re doing that kind of business with because otherwise you know things can happen and i think we’ve all heard those stories of things happening product disappearing or the yields being low or not understanding what’s actually happening people get upset people you know call their lawyers and then next thing you know somebody’s unhappy and somebody’s a little happier but still nobody wins whenever the lawyers get involved it seems like so uh thank you jeff that was amazing now minor cannabinoids let’s let’s go right into it two years ago three years ago we knew they were out there nobody seemed like they were isolating them nobody seemed like they were doing anything with them thc and cbd ruled the market and really in the cannabis side beforehand thc was the product right even even even if you wanted cbd it was hard to find four years ago five years ago what are we seeing in the innovation side of minor cannabinoids in the space and how has that impacted the business that you all operate because i can understand starting out in the pesticides remediation and but the market is changing very quickly what are you all seeing michelle jeff take it i i i i’m not sure who’s the right person to answer this but it’s been a a a massive shift um to these minor cannabinoids michelle why don’t you start and then i’ll finish with you yeah so we are definitely seeing um you know people are wanting to um you know so delta eight delta nine um cbn cbg so you know yeah there’s definitely um you know interest in in that and the nice thing is that we do have um a smaller benchtop system with um the smaller columns to basically do the um the r d for that you know we have um we are working on applications and so we’re able to um you know like you know really good starting points on most of them so um and the fact that we have um internship have us over 30 different bonded phases um and different particle sizes so we really have you know all the like all the correct tools to like really um you know kind of utilize for this and the particle sizes that’s that’s for the medium right or the media right is that what you’re talking about yes correct okay yeah sorry yes no no i just want to break it down not everybody listening would have known what that meant so in the column you have 30 different molecules that can go in there and a tr like you’re like jeff was saying attract things at a different rate um to be able to separate them yes cool sorry yeah correct yeah so we basically have we just have a lot of options as it when it comes to columns so there’s not just one type of column there’s all different types of columns that can be used for all different types of things so yeah so we do have the option the smaller benchtop unit that we have is higher pressure so it can handle you know the the smaller particle size because when you decrease that you it increases the back pressure so it’s good to have flexibility with that great and when it comes to minor cannabinoids specifically what all are you able to isolate does it include you know the cbc’s and the cbts and the cbga like all like the list is endless not that they’re all very highly present in the plant but the list is endless what what all are you all able to isolate um in through this process so i’ll let me take that um the when it comes to chromatography you can what it’s the science of separation okay so we can separate anything in liquid chromatography um the um the outcome though if it’s really difficult to separate the two molecules then the outcome is yield you’re going to have lower yield okay and i i’m not i think the best example i can give right now is the delta 8 and delta 9 thc because these are isomers it’s essentially the same molecule but there’s just one position where you’ve altered that structure so they’re essentially the same so separating those is very difficult but it can be done you know when you for example when you send out your product your potency testing and your and the the the result that you get back is you’ve got you know x percent of delta eight and another percent of delta nine they’re using the exact same technology um in chromatography to separate those on a very small scale so the fact that you can separate on a small scale you can do on a large scale it’s just a matter of throughput how much are you going to be able to do through put in time right as far as it is yeah so the the short answer is it can be done it’s just a matter of yield so we’re um we’re you know there’s always a way and we’re currently working on delta eight thc we’re we’ve got pretty much an application like michelle said we’ve got really good starting points like for cbc that’s a really high value one that we pretty much got completed but all of these can be done and i think the big shift that we’ve seen in the marketplace for these miners is is synthesis now in the the cannabis marketplace you’re applying the same knowledge that has been done in pharmaceutical development because that’s what they’ve been doing they’re taking a molecule they’re they’re changing it they’re doing some form of synthesis to change it just like you can convert cbd into delta eight thc or cbn for that matter so what we’re finding now is there’s a real shift in the marketplace where people now are realizing okay we have to use the same tools that have been done in pharmaceutical r d and apply those to cannabis to create these new novel molecules because when it comes to cbd i mean i think the industry is figured out very quickly and very efficiently how to extract cbd right i would have to say having been to many of these facilities they could do it at a really high scale it’s a matter of converting those into some of these minors we’ve also seen so you know a lot of people have fear around yeast produced molecules which i know has done a fair amount in the pharmaceutical industry but in the cannabis industry a lot of people are you know um not not vibing let’s just say with the yeast produced molecules but some people are ex very excited about it because you can produce a lot of these minor cannabinoids on a much greater scale even though it may cost a little bit more money um and uh facility build out what what’s your opinion on the yeast produced uh cannabinoids what have you learned there michelle jeff take it away i’m just curious what your opinion is i know this doesn’t really have too much to do with equipment but i’m sure you all are watching the space well it actually does have to do with our equipment because we do have clients using the yeast process and they have to do the same they have to purify it so they are using our equipment for that uh i think it’s i mean you know personally my opinion i think it’s going to have the same stigma that gmo does in the foods industry you know there’s a certain group of people who just don’t care if it’s gmo but i think there’s a growing body of people that are a bit against gmo so i think we’re going to see a little bit of both i’ll come out and say it i’m excited about it because like you can produce some of these molecules in the plant at a very high concentration right and converting that can be really expensive so if we can you know tap into some of these miter cannabinoids that there’s just really no good way to produce them right now and get the r d done and then learn about the molecule i think it’s just super exciting i i i think everybody else is kind of worried about you know the impact on the space but i think to be able to learn is really important for this space and for humanity and the industry to be able to see what effect these products have so i’m really excited about it i’m so curious about it i want to learn more but uh let’s see when it comes to like you’ve got a lab right and they’re doing large-scale crude distillate extraction um one or the other they call you up what’s the most important thing they should be considering whenever they want to talk about chromatography equipment and um isolation of molecules like how does that conversation usually go what in what are the things that you see that they miss that they should really be asking about for anybody that’s thinking about buying this type of equipment what what are the big considerations because it’s not cheap you know i don’t know exactly what y’all’s prices are you know to get a base set up and you all can speak to that better than i can what are the questions that they should be asking to really understand if this is the route that they should go why don’t you take that so um so one of the main questions that um especially you know with thc remediation in-house analytical is not not me having hplc is not like super important because you’re only sending out like like maybe five fractions like every other week or so um but with um if you’re doing minor cannabinoids in-house analytical is really important um just because it’s just a time saver so you know for you to be able to just you know just throw whatever comes off our system and throw it onto an hplc to basically confirm what you have um it’s just a huge time saver and will you know basically help them in the whole process so yeah so and you know our system is very easy to use but an hplc system does require a little bit more skill so it’s just going to be a matter of you know having someone like a skilled person to be able to to to run that system you know so in-house analytic um you know party testing is great but again it’s just it’s going to be the time you know costly and also you know over time and then the time restraint so basically how long you have to wait for that results to come back so yeah so that’s one thing that we do um you know basically if you are going to be doing this you know please look into getting in-house analytical or an hplc system it doesn’t matter what third party you use it takes time if you can just stick it in the machine let it run through the little mini column flash a light at it or whatever they do to figure out what’s in there and know within you know 20 minutes that that would be better right yeah no that’s interesting i hadn’t thought about that because you know if for anybody listening out there what michelle is saying if you’re thinking about doing chromatography you’re also going to need to learn about hplcs and in-house testing um to be efficient uh jeff do you have do you have anything to add to that question what should they be thinking about or asking uh whenever they’re they’re they’re exploring this path it’s i think the questions that we’ll ask is okay where where do you want to be tomorrow and where do you want to be a year from now in terms of your feedstock you know what how much do you want to be processing tomorrow and how much a year from now because it’s really important to know that so that we can spec out the right set of equipment you know that way we can you know you can grow with them you may you know a lot of times people will call up they say what’s the biggest one you got and we just pump the brakes a little and say you know let’s we have everything you need but do you really need the biggest piece of hardware that you’ve got right now 90 of the time you don’t so let’s start with the smaller unit and then dial in that process for your current throughput demand and then either upgrade that with a larger column or consider adding a second piece of equipment on down the road because that smaller unit is always going to be useful you can use that to qualify large batches of material you can use it as michelle mentioned for r d purposes so you know it’s that’s the question we’ll ask we want to know you know current and future so that we can you know manage the expectations and also not over supply you know uh and i’m sure you’ve seen it a lot of people highly over invested in equipment and yeah um and you’ll see secondary you know sales of this equipment after somebody failed or had issues or for whatever reason and a lot of it is massive massive equipment some of the most efficient operations that i’ve been to utilize multiple small machines because if one goes down the whole production facility doesn’t go down and if you don’t need the big machine right out of the gate why buy the big machine right at the gate why you know and i you there might be a reason and you probably know better but why do you need the big machine at all get a bunch of smaller machines so that the maintenance schedule can happen and you don’t have to shut down your whole facility to do that uh it’s it’s kind of um i think it was a big learning that the space went through was to be a little bit more cautious just because you have money in the bank and investors and this and that take take your time with scaling up production because if you don’t have sales you don’t need the product right and i think you’ve probably seen a fair amount of that and had to have those same conversations we have um with with some of the people that were doing really big things but maybe we did a little bit you know what a little bit too big too early um right and paid a steep price for that so michelle who you’ve got somebody out in boulder colorado how many of those uh 420s yeah eleven they have eleven systems and they do tolling yeah is 420 the large size no the smallest one the smallest right yeah and they’re probably really efficient with it too right because they can take one offline and barely lose any they lose 1 11 of their production capacity if one of them has some kind of issue and all equipment does at some point need maintenance right um what does the maintenance schedule look like for your kind of machinery and what can people expect for up time when it comes to production uh efficiency so we actually have a whole troubleshooting document and so basically like if any this happens this is what you do so it’s like a whole document and the nice thing is that all our fluidics are mostly external so it’s very user serviceable like our pump heads are right there so we know where like you know like the points that you’re gonna have to like maybe clean this once in a while so we have a you know in our sop we have like you know basically at the end of each day you have to like you know do a little cleaning like so you know we have um all that incorporated in our soapy and everything like that and basically detailed instructions and then we also have you know a full service team to to help them if they if they did need the help but majority of the time like night if they just like you know get like a phone call and be like oh hey what do i do i’m like oh just flush your lines and you know what i mean so like a lot of it can just can be just troubleshoot it over the phone and it’s like a quick fix if it’s not then you know there’s always support for them so right right um uh but it sounds like y’all are opening up an r d facility in new york uh i would love to learn a little bit more are you all just using that to learn or are you all actually producing a product for the market um in the cannabinoid space what what’s what’s the plan what’s the gameplan we were discussing that because we’ve applied for a license for the state of new york and that will allow us to have large amounts of material whether it be biomass or extract whatever and we’ll have that on site and the number one intent is to accelerate our applications development so that we can focus on these minor cannabinoids um it’ll also be used to for process development so we can improve upon our existing processes and then we are going to because we have not just these large scale chromatography instruments we actually have a whole suite of analytical instruments from hplc to icpms so icpms that’s used for metals testing so the heavy metals that you have to test for in the adult use phase eventually you’re gonna have to test for that in the the hemp space as well so we’ll have methodology for that and we’ll also be doing some con some testing some third-party testing because we have these capabilities but we’re not going to be focused on you know potency or anything like that it’s going to be more specialized applications that aren’t necessarily available by the standard third-party testing lives amazing amazing so we’re really excited about that we’re hoping to have our license done um we’ve already got the safe on order we will have a dea license as well so we’ll have a complete capability for that in new york hopefully in the next i think the schedule’s about three months out so if it’s three months out you need to add another 1.5 to that so let’s say let’s say uh 6.5 months i’m hoping we’ve already included that fudge factory i think it’s probably realistic to say okay we’ll get it done this year yeah this year right you know you’ve been in the space long enough and worked with enough people and regulators especially um with all of your clients you know the deal oh yeah it never it never seems to happen on a timeline when the government’s involved and the inspections are involved and all of that so good luck to you i’m excited to see what y’all are up to and keep innovating bringing those minor cannabinoids to the market helping many farmers with pesticides and thc remediation thank you for being in this space thank you for doing the interview and it was an exciting show i look forward to getting this out to the world you’re most welcome all right jeff michelle with interchan thank you so much thank you have a great day cheers.

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